ISSN 1662-4009 (online)

ey0019.9-4 | Metabolic risk in childhood cancer | ESPEYB19

9.4. Metabolic syndrome in male survivors of pediatric allogeneic hematopoietic stem cell transplantation: impact of total body irradiation, low-grade inflammation, and hypogonadism

E Muhic , S Mathiesen , MM Nielsen , A Suominen , K Sorensen , M Ifversen , RL Nolsoe , KM Pedersen , P Lahteenmaki , BG Nordestgaard , A Juul , K Jahnukainen , K Muller

klaus.mueller@regionh.dk Transplant Cell Ther. 2021 Sep;27(9): 778.e1-778.e8. PMID: 34091072.Brief Summary: Several studies in cancer survivors have reported an increased prevalence of metabolic syndrome (MetS), which is often observed in the absence of overt obesity. Data about MetS in survivors of pediatric hematopoietic stem cell transplantation (HSCT) are scarce. This cross-sectional cohort study...

ey0020.7-1 | Gonadal Function and Fertility Issues in Childhood Cancer Survivors | ESPEYB20

7.1. Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis: a retrospective study of a male fertility preservation cohort

I Masliukaite , E Ntemou , EAM Feijen , M van de Wetering , A Meissner , AT Soufan , S Repping , LMC Kremer , K Jahnukainen , E Goossens , AMM van Pelt

Brief summary: This multicentre retrospective cohort study evaluated testicular structure in 101 boys aged <14 years with solid tumors, CNS tumors, leukemia/lymphoma, or non-malignant hematological disorders, who were admitted for a fertility preservation programme between 2002 and 2018.The aim of the study was to clarify a possible role of the disease itself on the risk of infertility, independently of cancer therapies. Clinical data, testicular vol...